NextGenMap: fast and accurate read mapping in highly polymorphic genomes
نویسندگان
چکیده
منابع مشابه
NextGenMap: fast and accurate read mapping in highly polymorphic genomes
SUMMARY When choosing a read mapper, one faces the trade off between speed and the ability to map reads in highly polymorphic regions. Here, we report NextGenMap, a fast and accurate read mapper, which reduces this dilemma. NextGenMap aligns reads reliably to a reference genome even when the sequence difference between target and reference genome is large, i.e. highly polymorphic genome. At the...
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Correspondence: [email protected] Center for Bioinformatics, Saarland University, Campus E2.1, 66123, Saarbrücken, Germany Max Planck Institute for Informatics, Saarbrücken, Germany Full list of author information is available at the end of the article †Equal contributor Abstract Read-based phasing allows to reconstruct the haplotype structure of a sample purely from sequencing reads. ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btt468